But lets not forget the amazing night in the last round that saw Barca come back from 4-0 down in the first leg to go through.
They will be hoping once again for a bit of Lionel Messi magic tonight – their superstar of course starts the game.
What is the latest Barcelona news?
Defender Javier Macherano was a concern due to a calf injury, and only makes the bench for tonight’s second leg.
Samuel Umtit will partner Gerard Pique at the back.
Arda Turan hasn’t made it for the game due to a groin injury.
Luis Enrique's Barcelona face a tough task against Juventus on WednesdayRex Features
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What is the latest Juventus news?
Paulo Dyabala's fitness was in question but the Argentinian is fit again after training on Monday.
The rest of the team is expected to be unchanged from the team that played last week.
Max Allegri has his Juventus side set up ready to counter attack BarcelonaRex Features
Where can I watch Barcelona vs Juventus?
Barcelona vs Juventus will kick off at 7:45pm and you can watch it live on BT Sport 2.
Alternatively you can follow the action via SunSport's blog.
SunSport prediction
Barca shocked the world with their comeback against PSG in the last round - but Juve are a different class.
Enrique's players are going to have to go all out to overturn Juve's 3-0 lead but we can't see this happening.
Juve will pounce on the counter-attack and Juve will comforably be in the semi-finals.
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