And with rain forecast through the next eight hours until kick-off, it could dampen Argentina‘s hopes of getting a win through the silky skills of talisman Lionel Messi.
Messi and Co looked determined to make up for past mishaps as they arrived for what could be a career-defining international clash.
Led by their tactical maverick coach Jorge Sampaoli, the side are desperate for all three points against Antonio Valencia and Ecuador to make it to Russia.
A hugely disappointing campaign so far sees the 2014 World Cup finalists languishing in sixth place in South American qualifying.
But the good news for Messi and Sampaoli is that the table is still congested, with Chile third in the automatic qualifying places just a point ahead of them.
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That left Boca Junior’s 27-year-old forward Dario Benedetto to lead the line against the Peruvians – a player almost unheard of on the world stage.
Meanwhile Dybala was an unused substitute, as was the likes of Mauro Icardi.
They play at the Estadio Olimpico Atahualpa, a meagre 9,000ft above sea level – and the sort of lung-sapping conditions that makes a must-win game even harder.
Argentina headed to a hotel in Guayaquil before moving on to Quito for the match, with surely a tough night’s sleep ahead for some of the country’s superstars.
The likes of Angel Di Maria and Javier Mascherano were also in tow as the players marched into Ecuador with stern looks on their faces.
They know that if they fail to make it to Russia, tough questions will be asked from the demanding Argentinian public.
South American qualifying - final fixtures
ALL matches kick off at half past midnight on Tuesday morning UK time.
Brazil vs Chile
Ecuador vs Argentina
Paraguay vs Venezuela
Peru vs Colombia
Uruguay vs Bolivia
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