France will be without the services of Matthieu Jalibert, Antoine Dupont and Kévin Gourdon after they were all sidelined through injury.
19-year-old Jalibert, who made his Test debut in Saturday's dramatic 15-13 loss to Ireland at the Stade de France in Paris, left the field after 30 minutes with a knee ligament injury that will keep him on the sidelines for the rest of the tournament.
The young fly-half has been replaced in head coach Jacques Brunel's squad by Lionel Beauxis, who could win his first France cap in six years, while his Lyon team-mate Baptiste Couilloud comes into the squad at scrum-half for Dupont, who has been ruled out for the rest of the season after tearing his anterior cruciate ligament.
Brunel has also called up back-row Louis Picamoles as a replacement for Gourdon who injured his ankle and is expected to be out for at least three weeks.
The French rugby federation (FFR) revealed the news of the players injuries via their Twitter account.
Après la rencontre de samedi et suite à des examens médicaux, @Matthieuu10 est forfait. Il est remplacé par Lionel Beauxis dans le groupe France qui prépare la rencontre face à l’Écosse. #FRAECO pic.twitter.com/QhGPYoiyqT
— FF Rugby (@FFRugby) February 4, 2018
— FF Rugby (@FFRugby) February 4, 2018
— FF Rugby (@FFRugby) February 4, 2018
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