England head coach Eddie Jones has named youngsters Nick Isiekwe and Tom Curry in the starting XV to face South Africa in Johannesburg.
Owen Farrell (Saracens) will captain the side while club-mate Mako Vunipola will run out for his 50th England cap.
Jones has included seven players in the starting XV who were involved in the Premiership final between Saracens and Exeter Chiefs two weekends ago.
Isiekwe (Saracens) will make his first start for England while two uncapped players – Brad Shields (Hurricanes/Wasps) and Ben Spencer (Saracens) – are named among the replacements.
“We have had a really good week in preparation for this weekend and we are pleased with the way the squad have come together,” said Jones.
“Owen Farrell has settled in well to his new role, with the senior players supporting him, and there is a good feeling within the camp. We want to do something special on this tour and the players are all incredibly excited about this challenge and opportunity we have.”
England: 15 Elliot Daly, 14 Jonny May, 13 Henry Slade, 12 Owen Farrell (c), 11 Mike Brown, 10 George Ford, 9 Ben Youngs, 8 Billy Vunipola, 7 Tom Curry, 6 Chris Robshaw, 5 Nick Isiekwe, 4 Maro Itoje, 3 Kyle Sinckler, 2 Jamie George, 1 Mako Vunipola
Replacements: 16 Luke Cowan-Dickie, 17 Joe Marler, 18 Harry Williams, 19 Brad Shields, 20 Nathan Hughes, 21 Ben Spencer, 22 Piers Francis, 23 Denny Solomona
Date: Saturday, June 9
Venue: Ellis Park, Johannesburg
Kick-off: 17:05 local (16:05 BST, 15:05 GMT)
Referee: Ben O’Keeffe (New Zealand)
Assistant Referees: Romain Poite (France), Glen Jackson (New Zealand)
TMO: Simon McDowell (Ireland)
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