Buffalo Bills vs. Indianapolis Colts NFL Week 11 Odds, Plays and Insights

Nov 20, 2021

Check out odds, plays and more for the Buffalo Bills vs. Indianapolis Colts NFL Week 11 matchup on November 21, 2021.

The Buffalo Bills (6-3) and Indianapolis Colts (5-5) will clash in Week 11 of the NFL season.

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Odds for Bills vs. Colts

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Buffalo and its opponents have gone over the current 49.5-point total in four of nine games this season.
Indianapolis' games have gone over 49.5 points in four of 10 chances this season.
Sunday's total is 8.4 points lower than the two team's combined 57.9 points per game average.
This contest's total is 11.5 points more than the 38 these two squads combine to allow per game this season.
Bills games have an average total of 49.3 points this season, 0.2 fewer than Sunday's over/under.
In 2020, games involving the Colts have averaged a total of 46.5 points, 3.0 fewer than this game's set over/under.

Buffalo has played nine games, with six wins against the spread.
The Bills are 4-1 ATS when favored by 7 points or more this season.
Buffalo's games this year have hit the over on four of nine set point totals (44.4%).
This year, the Bills average 8.1 more points per game (31.1) than the Colts give up (23.0).
When Buffalo scores more than 23.0 points, it is 6-1 against the spread and 6-1 overall.
The Bills average 401.1 yards per game, 37.5 more yards than the 363.6 the Colts give up per matchup.
Buffalo is 4-2 against the spread and 4-2 overall when the team churns out more than 363.6 yards.
This year, the Bills have 10 turnovers, 11 fewer than the Colts have takeaways (21).
Click over to SISportsbook and find the latest spread, moneyline and total for Buffalo's matchup with the Colts.

In Indianapolis' 10 games this year, it has six wins against the spread.
The Colts covered the spread in their only game when underdogs by 7 points or more.
Indianapolis' games this year have gone over the total in six out of 10 opportunities (60%).
The Colts rack up 26.8 points per game, 11.8 more than the Bills surrender (15.0).
Indianapolis is 6-4 against the spread and 5-5 overall when the team records more than 15.0 points.
The Colts collect 89.3 more yards per game (363.4) than the Bills allow per contest (274.1).
Indianapolis is 6-3 against the spread and 5-4 overall when the team totals more than 274.1 yards.
This year the Colts have 10 turnovers, 14 fewer than the Bills have takeaways (24).

Buffalo is 3-1 against the spread, and 3-1 overall, at home this season.
This year, as 7-point favorites or more at home, the Bills are 3-0 ATS.
Buffalo has hit the over once in four home games this season.
The average total in Bills home games this season is 47.3 points, 2.2 fewer than this outing's over/under (49.5).
Indianapolis is 2-2 overall, and 3-1 against the spread, on the road.
This season, in three of four away games Indianapolis has hit the over.
This season, Colts away games average 44.8 points, 4.7 fewer than this outing's over/under (49.5).