Buffalo Bills vs. Pittsburgh Steelers NFL Week 1 Odds, Plays and Insights


Check out odds, plays and more for the Buffalo Bills vs. Pittsburgh Steelers NFL Week 1 matchup on September 12, 2021.

Aug 28, 2021; Orchard Park, New York, USA; Buffalo Bills head coach Sean McDermott looks on against the Green Bay Packers during the second half at Highmark Stadium. Mandatory Credit: Rich Barnes-USA TODAY Sports

Oddsmakers give the Buffalo Bills (0-0) the advantage on Sunday, September 12, 2021 against the Pittsburgh Steelers (0-0). Buffalo is favored by 6.5 points. The total for this game has been set at 48 points.

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Buffalo Bills vs. Pittsburgh Steelers Game Info

  • Game Day: Sunday, September 12, 2021
  • Game Time: 1:00 PM ET
  • TV Channel: CBS
  • Location: Orchard Park, New York
  • Stadium: Highmark Stadium

Odds for Bills vs. Steelers

Over/under insights

  • Of 19 games last year, Buffalo played 11 with over 48 points scored, its current matchup's point total.
  • Last season, six of Pittsburgh's 17 matchups went over 48 total points scored.
  • The two teams averaged a combined 9.3 more points per game (57.3) a season ago than this matchup's over/under of 48 points.
  • The Bills and the Steelers saw their opponents average a combined 5.1 less points per game last season than the over/under of 48 set in this outing.
  • The average total the Bills had set in matchups last year was 0.2 more points than this outing's point total.
  • The average point total for the Steelers in 2020 was 3.1 points less than this game's over/under.

Bills stats and trends

  • Buffalo went 11-5-0 ATS last season.
  • The Bills covered the spread twice last season (2-2 ATS) when playing as at least 6.5-point favorites.
  • Click over to SISportsbook and place wagers on the Bills against the spread.
  • Buffalo and its opponents combined to go over the point total 11 out of 16 times last season.
  • The Bills scored 31.3 points per game last year, 11.8 more than the Steelers gave up per contest (19.5).
  • Buffalo was 11-4 against the spread and 13-2 overall last season when the team scored over 19.5 points.
  • The Bills averaged 90.6 more yards per game (396.4) than the Steelers allowed per matchup (305.8) last year.
  • When Buffalo amassed over 305.8 yards last season, the team was 11-6 against the spread and 14-3 overall.
  • Last season the Bills had 22 turnovers, five fewer than the Steelers had takeaways (27).

Steelers stats and trends

  • Pittsburgh compiled a 10-6-0 record against the spread last year.
  • The Steelers were an underdog by 6.5 points or more once last season, and covered the spread.
  • In Pittsburgh's games last year, the combined scoring went over the point total eight times.
  • Looking to place a bet on the over in this matchup? Check out SISportsbook and make your pick.
  • Last season the Steelers racked up just 2.6 more points per game (26.0) than the Bills allowed (23.4).
  • Pittsburgh was 9-3 against the spread and 11-1 overall in games when it recorded over 23.4 points last season.
  • The Steelers averaged just 17.9 fewer yards per game (334.6) than the Bills allowed per matchup (352.5) last season.
  • When Pittsburgh piled up more than 352.5 yards last season, the team was 7-3 against the spread and 8-2 overall.
  • The Steelers had 18 giveaways last season, while the Bills had 26 takeaways.

Bills Top Players

  • Josh Allen recorded 4,544 passing yards (284.0 yards per game) with a 69.2% completion percentage last year (396-of-572), while throwing 37 touchdowns and 10 interceptions. He also tacked on 421 rushing yards on 102 carries with eight touchdowns, averaging 26.3 yards per game.
  • Check out SISportsbook for player prop bets for Allen and his teammates, then place your bets.
  • Devin Singletary took 156 carries for 687 rushing yards a season ago (42.9 yards per game) while scoring two touchdowns. He also caught 38 passes for 269 yards (16.8 receiving yards per game).
  • Last season Zack Moss ran for 481 yards on 112 carries (30.1 ypg), with four rushing touchdowns.
  • Stefon Diggs grabbed 127 passes for 1,535 yards last season and scored eight touchdowns. He was targeted 166 times and averaged 95.9 yards per game.
  • Cole Beasley also chipped in with 82 grabs for 967 yards and four touchdowns last year. He was targeted 107 times and put up 60.4 receiving yards per game.
  • Last year Emmanuel Sanders caught 61 passes on 82 targets for 726 yards and five touchdowns, averaging 51.9 receiving yards per game.

Steelers Top Players

  • Last year Ben Roethlisberger recorded 3,803 passing yards (237.7 yards per game) while going 399-for-608 (65.6% completion percentage) and throwing 33 touchdowns and 10 interceptions.
  • A season ago, Benny Snell Jr. churned out 368 rushing yards (23.0 yards per game) and scored four touchdowns.
  • Kalen Ballage amassed 303 rushing yards on 91 carries (25.3 yards per game), with three touchdowns on the ground last season.
  • Diontae Johnson grabbed 88 passes for 923 yards last season with seven touchdowns. He was targeted 144 times, and averaged 57.7 yards per game.
  • Find the latest odds and place your bets on Johnson to hit his player props at SISportsbook.
  • Chase Claypool added 873 yards on 62 catches and nine touchdowns. He was targeted 109 times and averaged 54.6 receiving yards per game last year.
  • JuJu Smith-Schuster collected 831 yards on 97 catches with nine touchdowns in 2020, averaging 51.9 yards per game (on 128 targets).

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