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Buffalo Bills vs. Tennessee Titans NFL Week 6 Odds, Plays and Insights

Check out odds, plays and more for the Buffalo Bills vs. Tennessee Titans NFL Week 6 matchup on October 18, 2021.

Oct 3, 2021; Orchard Park, New York, USA; Buffalo Bills running back Devin Singletary (26) finds a hole to run against the Houston Texans in the fourth quarter at Highmark Stadium. Mandatory Credit: Mark Konezny-USA TODAY Sports

The top teams from opposing divisions meet when the AFC East-leading Buffalo Bills (4-1) hit the field as a 5.5-point favorite against the AFC South-leading Tennessee Titans (3-2) on Monday, October 18, 2021 at Nissan Stadium. A total of 54 points has been set for this matchup.

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Odds for Bills vs. Titans

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Over/under insights

  • Buffalo's games this season have gone over 54 points three of six times.
  • Tennessee's games have gone over 54 points in two opportunities this season.
  • The two teams combine to score 60.8 points per game, 6.8 more than the over/under in this contest.
  • This contest's over/under is 15.2 points above the 38.8 these two squads combine to allow per game this season.
  • The Bills and their opponents score an average of 49.0 points per game, 5.0 fewer than Monday's total.
  • The 54 total in this game is 4.4 points higher than the 49.6 average total in Titans games this season.

Bills stats and trends

  • In Buffalo's five games this season, it has five wins against the spread.
  • This season, the Bills have two ATS wins in three games as a favorite of 5.5 points or more.
  • Buffalo's games this year have hit the over on two of six set point totals (33.3%).
  • This year, the Bills put up 8.4 more points per game (34.4) than the Titans allow (26).
  • When Buffalo records more than 26 points, it is 5-0 against the spread and 4-0 overall.
  • The Bills collect 33 more yards per game (410.4) than the Titans give up per contest (377.4).
  • In games that Buffalo amasses over 377.4 yards, the team is 4-0 against the spread and 3-0 overall.
  • The Bills have four turnovers this season, equal to the number of takeaways for the Titans.
  • Click over to SISportsbook and find the latest spread, moneyline and total for Buffalo's matchup with the Titans.

Titans stats and trends

  • Tennessee has three wins against the spread in five games this year.
  • The Titans covered the spread in their only game when underdogs by 5.5 points or more.
  • Tennessee's games this year have eclipsed the over/under three times in five opportunities (60%).
  • The Titans average 13.6 more points per game (26.4) than the Bills allow (12.8).
  • Tennessee is 3-2 against the spread and 3-2 overall when the team puts up more than 12.8 points.
  • The Titans collect 389.2 yards per game, 137.4 more yards than the 251.8 the Bills allow.
  • When Tennessee piles up over 251.8 yards, the team is 3-1 against the spread and 3-1 overall.
  • This year the Titans have seven turnovers, eight fewer than the Bills have takeaways (15).

Home and road insights

  • The average total in Titans home games this season is 50.5 points, 3.5 fewer than this outing's over/under (54).
  • Buffalo is 3-0 overall, and 3-0 against the spread, in away games.
  • This season, in three road games, Buffalo has hit the over once.
  • Bills away games this season average 52.3 total points, 1.7 fewer than this contest's over/under (54).

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