Check out odds, insights and more in our betting preview for the Buffalo Bulls vs. Old Dominion Monarchs college football matchup on September 25, 2021.

The Buffalo Bulls (1-2) are double-digit, 13.5-point favorites heading into their matchup on Saturday, September 25, 2021 against the Old Dominion Monarchs (1-2). The over/under is set at 51.5.
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Odds for Buffalo vs. Old Dominion
Odds courtesy of SI Sportsbook.
Over/Under Insights
- Old Dominion and its opponents have combined to score more than 51.5 points in all three games this season.
- The combined points per game average of the two teams, 57, is 5.5 points above Saturday's over/under.
- This contest's over/under is 0.8 points under the 52.3 these two squads combine to give up per game in 2021.
- The average total in Bulls games this season is 56.3, 4.8 points above Saturday's total of 51.5.
- The 57.2 PPG average total in Monarchs games this season is 5.7 points more than this game's over/under.
Buffalo Stats and Trends
- Buffalo has one win against the spread in three games this season.
- The Bulls rack up just 1.0 more point per game (32.3) than the Monarchs surrender (31.3).
- The Bulls rack up 445.3 yards per game, 124.3 more yards than the 321.0 the Monarchs give up per matchup.
- Buffalo is 1-1 against the spread and 1-2 overall when the team picks up over 321.0 yards.
- The Bulls have two giveaways this season, while the Monarchs have two takeaways .
- Find the latest spread and moneyline odds for Buffalo at SISportsbook.
Old Dominion Stats and Trends
- Old Dominion has one win against the spread in three games this year.
- The Monarchs have been underdogs by 13.5 points or more two times this year and have not covered the spread once.
- Old Dominion's games this year have gone over the point total one time in three opportunities (33.3%).
- This season the Monarchs put up 3.7 more points per game (24.7) than the Bulls give up (21.0).
- The Monarchs collect just 4.0 fewer yards per game (348.3) than the Bulls give up per matchup (352.3).
- The Monarchs have turned the ball over three times this season, one more turnover than the Bulls have forced (2).
- Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.