Check out odds, insights and more in our betting preview for the Iowa State Cyclones vs. Baylor Bears college football matchup on September 25, 2021.

The No. 14 Iowa State Cyclones (2-1, 0-0 Big 12) are touchdown favorites when they visit the Baylor Bears (3-0, 0-0 Big 12) in a Big 12 matchup on Saturday, September 25, 2021 at McLane Stadium. The point total for the contest is set at 47.5.
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Odds for Iowa State vs. Baylor
Odds courtesy of SI Sportsbook.
Over/Under Insights
- Baylor's games have gone over 47.5 points in all three opportunities this season.
- The two teams combine to score 73.7 points per game, 26.2 more than the total in this contest.
- This contest's total is 22.9 points greater than the 24.6 these two squads combine to allow per game this season.
- The Cyclones and their opponents have scored an average of 49.0 points per game in 2021, 1.5 more than Saturday's total.
- The 52.2 PPG average total in Bears games this season is 4.7 points more than this game's over/under.
Iowa State Stats and Trends
- So far this year Iowa State has one win against the spread.
- The Cyclones have been favored by 7 points or more once this season and covered the spread.
- The Cyclones average 15.7 more points per game (27.0) than the Bears give up (11.3).
- Iowa State is 1-1 against the spread and 2-1 overall this season when the team notches more than 11.3 points.
- The Cyclones rack up 161.7 more yards per game (389.0) than the Bears give up per outing (227.3).
- In games that Iowa State picks up more than 227.3 yards, the team is 1-1 against the spread and 2-1 overall.
- The Cyclones have five giveaways this season, while the Bears have five takeaways .
- Find the latest spread and moneyline odds for Iowa State at SISportsbook.
Baylor Stats and Trends
- Thus far this year Baylor has two wins against the spread.
- Baylor's games this year have hit the over two times in three opportunities (66.7%).
- This year the Bears score 33.4 more points per game (46.7) than the Cyclones allow (13.3).
- When Baylor scores more than 13.3 points, it is 2-1 against the spread and 3-0 overall.
- The Bears collect 366.0 more yards per game (558.7) than the Cyclones allow per contest (192.7).
- Baylor is 2-1 against the spread and 3-0 overall when the team piles up over 192.7 yards.
- The Bears have three turnovers this season, equal to the number of takeaways for the Cyclones.
- Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.