Check out odds, insights and more in our betting preview for the Iowa Hawkeyes vs. Colorado State Rams college football matchup on September 25, 2021.

The No. 5 Iowa Hawkeyes (3-0) are massive 23.5-point favorites on Saturday, September 25, 2021 against the Colorado State Rams (1-2). The point total is 44.5.
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Odds for Iowa vs. Colorado State
Odds courtesy of SI Sportsbook.
Over/Under Insights
- Iowa and its opponents have not yet combined for more than 44.5 points -- this matchup's over/under -- in a game this year.
- The combined points per game average of the two teams, 52.3, is 7.8 points more than Saturday's over/under.
- This contest's over/under is 10.5 points above the 34 these two squads combine to allow per game this season.
- Hawkeyes games this season feature an average total of 49.0 points, a number 4.5 points higher than Saturday's over/under.
- In 2021, games involving the Rams have averaged a total of 55.5 points, 11.0 more than the set over/under in this contest.
Iowa Stats and Trends
- Thus far this year Iowa is undefeated against the spread.
- Iowa's games this year have not hit the over on any of three set point totals.
- The Hawkeyes average 30.3 points per game, 6.3 more than the Rams allow per outing (24.0).
- Iowa is 3-0 against the spread and 3-0 overall in games when it records more than 24.0 points.
- The Hawkeyes collect 68.3 fewer yards per game (298.0), than the Rams give up per matchup (366.3).
- The Hawkeyes have turned the ball over two more times (3 total) than the Rams have forced a turnover (1) this season.
- Find the latest spread and moneyline odds for Iowa at SISportsbook.
Colorado State Stats and Trends
- Colorado State has one win against the spread in three games this season.
- The Rams score 22.0 points per game, 12.0 more than the Hawkeyes give up (10.0).
- Colorado State is 1-1 against the spread and 1-2 overall in games when it puts up more than 10.0 points.
- The Rams collect 130.0 more yards per game (408.7) than the Hawkeyes allow (278.7).
- When Colorado State churns out more than 278.7 yards, the team is 1-1 against the spread and 1-2 overall.
- This season the Rams have four turnovers, four fewer than the Hawkeyes have takeaways (8).
- Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.