Los Angeles Rams vs. San Francisco 49ers NFL Week 18 Odds, Plays and Insights


Check out odds, plays and more for the Los Angeles Rams vs. San Francisco 49ers NFL Week 18 matchup on January 9, 2022.

Sep 12, 2021; Detroit, Michigan, USA; San Francisco 49ers running back Elijah Mitchell (25) celebrates after scoring a touchdown during the second quarter against the Detroit Lions at Ford Field. Mandatory Credit: Raj Mehta-USA TODAY Sports

The Los Angeles Rams (12-4) will aim to extend their five-game winning run in a Week 18 clash against the San Francisco 49ers (9-7).

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Odds for Rams vs. 49ers

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Over/under insights

  • Los Angeles and its opponents have gone over the current 44-point total in 12 of 16 games (75%) this season.
  • In 62.5% of San Francisco's games this season (10/16), the teams combined to score more than Sunday's over/under of 44.
  • The two teams combine to average 52.3 points per game, 8.3 more than the over/under in this contest.
  • These two squads combine to surrender 42.9 points per game, 1.1 fewer than this contest's over/under.
  • Rams games this season feature an average total of 49.7 points, a number 5.7 points higher than Sunday's over/under.
  • The 44-point over/under for this game is 2.9 points below the 46.9 points per game average total in 49ers games this season.

Rams stats and trends

  • Los Angeles has played 16 games, with eight wins against the spread.
  • So far this season, the Rams have been installed as favorites by a 4-point margin or more nine times and are 4-5 ATS in those matchups.
  • Los Angeles' games this year have hit the over on eight of 16 set point totals (50%).
  • The Rams score 27.3 points per game, 6.0 more than the 49ers surrender per contest (21.3).
  • Los Angeles is 7-4 against the spread and 10-1 overall in games when it records more than 21.3 points.
  • The Rams rack up 66.0 more yards per game (378.8) than the 49ers give up per matchup (312.8).
  • In games that Los Angeles picks up more than 312.8 yards, the team is 8-7 against the spread and 12-3 overall.
  • The Rams have turned the ball over three more times (21 total) than the 49ers have forced a turnover (18) this season.
  • Click over to SISportsbook and find the latest spread, moneyline and total for Los Angeles' matchup with the 49ers.

49ers stats and trends

  • San Francisco has played 16 games, with eight wins against the spread.
  • The 49ers have been underdogs by 4 points or more one time this season and have not covered the spread once.
  • San Francisco's games this year have gone over the point total in 43.8% of its opportunities (seven times in 16 games with a set point total).
  • The 49ers rack up 3.4 more points per game (25.0) than the Rams surrender (21.6).
  • San Francisco is 7-3 against the spread and 8-2 overall in games when it scores more than 21.6 points.
  • The 49ers average 32.7 more yards per game (371.1) than the Rams allow per contest (338.4).
  • San Francisco is 5-4 against the spread and 6-3 overall when the team totals more than 338.4 yards.
  • This season the 49ers have 22 turnovers, one fewer than the Rams have takeaways (23).

Home and road insights

  • Los Angeles is 5-2 overall, and 4-3 against the spread, at home.
  • At home, the Rams are 3-2 ATS as 4-point favorites or greater.
  • In three of seven games at home this year, Los Angeles has gone over the total.
  • The average point total in Rams home games this season is 50.6 points, 6.6 more than this contest's over/under (44).
  • On the road, San Francisco is 5-3 overall and 4-4 against the spread.
  • The 49ers have two wins ATS (2-1) on the road as 4-point underdogs or more.
  • In eight away games this year, San Francisco has hit the over three times.
  • 49ers away games this season average 46.1 total points, 2.1 more than this contest's over/under (44).

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