Los Angeles Rams vs. San Francisco 49ers NFL Week 18 Odds, Plays and Insights


Check out odds, plays and more for the Los Angeles Rams vs. San Francisco 49ers NFL Week 18 matchup on January 9, 2022.

Sep 12, 2021; Detroit, Michigan, USA; San Francisco 49ers running back Elijah Mitchell (25) celebrates after scoring a touchdown during the second quarter against the Detroit Lions at Ford Field. Mandatory Credit: Raj Mehta-USA TODAY Sports

The Los Angeles Rams (12-4) will attempt to continue their five-game winning run versus the San Francisco 49ers (9-7) in Week 18.

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Odds for Rams vs. 49ers

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Over/under insights

  • Los Angeles and its opponents have gone over the current 44.5-point total in 10 of 16 games this season.
  • San Francisco and its opponents have combined to score more than 44.5 points in nine of 16 games this season.
  • The two teams combine to average 52.3 points per game, 7.8 more than the total in this contest.
  • The 42.9 combined points per game that these two squads have allowed this season are 1.6 fewer than the 44.5 over/under in this contest.
  • The Rams and their opponents have scored an average of 49.7 points per game in 2021, 5.2 more than Sunday's total.
  • The 46.9 PPG average total in 49ers games this season is 2.4 points more than this game's over/under.

Rams stats and trends

  • Los Angeles has eight wins against the spread in 16 games this season.
  • The Rams have an ATS record of 4-4 in their eight games as a favorite of 4.5 points or more so far this season.
  • Los Angeles' games this year have hit the over on eight of 16 set point totals (50%).
  • This year, the Rams score 6.0 more points per game (27.3) than the 49ers give up (21.3).
  • When Los Angeles puts up more than 21.3 points, it is 7-4 against the spread and 10-1 overall.
  • The Rams collect 378.8 yards per game, 66.0 more yards than the 312.8 the 49ers allow per contest.
  • Los Angeles is 8-7 against the spread and 12-3 overall when the team totals more than 312.8 yards.
  • The Rams have turned the ball over 21 times this season, three more turnovers than the 49ers have forced (18).
  • Click over to SISportsbook and find the latest spread, moneyline and total for Los Angeles' matchup with the 49ers.

49ers stats and trends

  • San Francisco has eight wins against the spread in 16 games this season.
  • This season, the 49ers are winless ATS when entering a game as an underdog of 4.5 points or more.
  • San Francisco's games this season have gone over the total in seven out of 16 opportunities (43.8%).
  • The 49ers average 25.0 points per game, 3.4 more than the Rams allow (21.6).
  • San Francisco is 7-3 against the spread and 8-2 overall in games when it scores more than 21.6 points.
  • The 49ers average 32.7 more yards per game (371.1) than the Rams give up per matchup (338.4).
  • When San Francisco totals more than 338.4 yards, the team is 5-4 against the spread and 6-3 overall.
  • The 49ers have 22 giveaways this season, while the Rams have 23 takeaways.

Home and road insights

  • At home this season, Los Angeles is 5-2 overall and 4-3 against the spread.
  • The Rams are 3-2 ATS as 4.5-point favorites or greater at home.
  • This season, in seven games at home, Los Angeles has gone over the total three times.
  • This season, Rams home games average 50.6 points, 6.1 more than this matchup's over/under (44.5).
  • This season in away games, San Francisco is 4-4 against the spread and 5-3 overall.
  • The 49ers have one win ATS (1-1) as 4.5-point underdogs or more away from home.
  • In eight road games this year, San Francisco has gone over the total three times.
  • The average point total in 49ers away games this season is 46.1 points, 1.6 more than this contest's over/under (44.5).

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