Louisville vs. Florida State College Football Odds, Plays and Insights


Check out odds, insights and more in our betting preview for the Louisville Cardinals vs. Florida State Seminoles college football matchup on September 25, 2021.

Sep 17, 2021; Louisville, Kentucky, USA; Louisville Cardinals head coach Scott Satterfield (right) celebrates a touchdown with tight end Francis Sherman (left) against the UCF Knights during the second half at Cardinal Stadium. Mandatory Credit: Jamie Rhodes-USA TODAY Sports

Oddsmakers project a tight contest when the Louisville Cardinals (2-1, 0-0 ACC) visit the Florida State Seminoles (0-3, 0-0 ACC) on Saturday, September 25, 2021 in a matchup between ACC opponents at Bobby Bowden Field at Doak Campbell Stadium. Louisville is favored by 1.5 points. The contest has a 61.5-point over/under.

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Odds for Louisville vs. Florida State

Odds courtesy of SI Sportsbook.

Over/Under Insights

  • Florida State has combined with its opponents to score more than 61.5 points in one game this season.
  • The combined points per game average of the two teams, 55, is 6.5 points fewer than Saturday's over/under.
  • This contest's over/under is 2.5 points above the 59 these two squads combine to surrender per game this season.
  • Cardinals games this season feature an average total of 64.8 points, a number 3.3 points higher than Saturday's over/under.
  • In 2021, games involving the Seminoles have averaged a total of 58.5 points, 3.0 fewer than this game's set over/under.

Louisville Stats and Trends

  • Louisville has covered the spread on one occasion this season.
  • This season, the Cardinals are winless against the spread when entering a game as a favorite of 1.5 points or more.
  • The Cardinals score the same number of points per game that the Seminoles allow (32.0).
  • The Cardinals average only 10.6 more yards per game (432.3) than the Seminoles allow per matchup (421.7).
  • When Louisville churns out over 421.7 yards, the team is 1-1 against the spread and 2-0 overall.
  • This year, the Cardinals have turned the ball over four times, while the Seminoles have forced four.
  • Find the latest spread and moneyline odds for Louisville at SISportsbook.

Florida State Stats and Trends

  • So far this year Florida State has one win against the spread.
  • This year, the Seminoles have one ATS win in two games as an underdog of 1.5 points or more.
  • Florida State's games this season have gone over the point total one time in three opportunities (33.3%).
  • The Seminoles score 23.0 points per game, 4.0 fewer than the Cardinals give up (27.0).
  • The Seminoles rack up 42.0 fewer yards per game (364.7) than the Cardinals give up (406.7).
  • The Seminoles have turned the ball over six more times (10 total) than the Cardinals have forced a turnover (4) this season.
  • Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.

Season Stats