Louisville vs. Florida State College Football Odds, Plays and Insights


Check out odds, insights and more in our betting preview for the Louisville Cardinals vs. Florida State Seminoles college football matchup on September 25, 2021.

Sep 17, 2021; Louisville, Kentucky, USA; Louisville Cardinals head coach Scott Satterfield (right) celebrates a touchdown with tight end Francis Sherman (left) against the UCF Knights during the second half at Cardinal Stadium. Mandatory Credit: Jamie Rhodes-USA TODAY Sports

Oddsmakers project a tight contest when the Louisville Cardinals (2-1, 0-0 ACC) visit the Florida State Seminoles (0-3, 0-0 ACC) on Saturday, September 25, 2021 in a matchup between ACC opponents at Bobby Bowden Field at Doak Campbell Stadium. Louisville is favored by 1.5 points. The contest has a point total set at 61.5.

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Odds for Louisville vs. Florida State

Odds courtesy of SI Sportsbook.

Over/Under Insights

  • Florida State has combined with its opponents to score more than 61.5 points in one game this season.
  • The two teams combine to average 55 points per game, 6.5 less than the over/under in this contest.
  • The 59 combined points per game that these two squads have allowed this season are 2.5 fewer than the 61.5 over/under in this contest.
  • The Cardinals and their opponents have scored an average of 64.8 points per game in 2021, 3.3 more than Saturday's total.
  • The 61.5 over/under in this game is 3.0 points higher than the 58.5 average total in Seminoles games this season.

Louisville Stats and Trends

  • Louisville has covered the spread on one occasion this year.
  • This season, the Cardinals are winless against the spread when entering a game as a favorite of 1.5 points or more.
  • The Cardinals put up the same number of points per game that the Seminoles surrender (32.0).
  • The Cardinals average only 10.6 more yards per game (432.3) than the Seminoles give up per matchup (421.7).
  • When Louisville piles up over 421.7 yards, the team is 1-1 against the spread and 2-0 overall.
  • The Cardinals have four giveaways this season, while the Seminoles have four takeaways .
  • Find the latest spread and moneyline odds for Louisville at SISportsbook.

Florida State Stats and Trends

  • Thus far this year Florida State has one win against the spread.
  • The Seminoles have covered the spread once this year when underdogs by 1.5 points or more (in two chances).
  • Florida State's games this year have gone over the total in one out of three opportunities (33.3%).
  • The Seminoles score 4.0 fewer points per game (23.0) than the Cardinals give up (27.0).
  • The Seminoles collect 42.0 fewer yards per game (364.7) than the Cardinals give up (406.7).
  • The Seminoles have turned the ball over 10 times this season, six more turnovers than the Cardinals have forced (4).
  • Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.

Season Stats