Check out odds, plays and more for the New England Patriots vs. New Orleans Saints NFL Week 3 matchup on September 26, 2021.

The New Orleans Saints (1-1) will try to prove oddsmakers wrong when they take on the New England Patriots (1-1) on Sunday, September 26, 2021 as 3-point underdogs. The total for this game has been set at 42 points.
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Odds for Patriots vs. Saints
Odds courtesy of SI Sportsbook.
Over/under insights
- New England played eight games with more than 42 points scored, its current matchup's over/under, last year.
- Last year, 11 of New Orleans' 18 matchups went over 42 total points scored.
- The Patriots and the Saints combined to average 8.5 more points per game a season ago than the over/under of 42 set for this matchup.
- Opponents of the two teams averaged a combined 1.2 more points per game last season (43.2) than this game's total of 42 points.
- The average point total in Patriots games last year was 2.8 more points than the over/under of 42 in this matchup.
- The average over/under in Saints games in 2020 was 5.8 more points than the point total of 42 for this outing.
Patriots stats and trends
- New England went 7-9-0 ATS last season.
- The Patriots had an ATS record of 3-3 when playing as at least 3-point favorites last season.
- New England's games went over the point total five out of 16 times last season.
- The Patriots scored just 0.7 fewer points per game (20.4) than the Saints surrendered (21.1) last season.
- New England was 4-2 against the spread and 5-1 overall last season when the team put up over 21.1 points.
- The Patriots averaged 327.3 yards per game last year, just 16.4 more than the 310.9 the Saints gave up per outing.
- In games that New England amassed more than 310.9 yards last year, the team was 4-4 against the spread and 4-4 overall.
- Last season the Patriots had 19 turnovers, seven fewer than the Saints had takeaways (26).
- Click over to SISportsbook and get the latest odds on this matchup.
Saints stats and trends
- New Orleans covered nine times in 16 games with a spread last season.
- The Saints covered the spread when playing as at least 3-point underdogs in their only opportunity last season.
- Last year, 10 of New Orleans' games hit the over.
- The Saints averaged 30.1 points per game last year, eight more than the Patriots surrendered (22.1).
- New Orleans was 8-6 against the spread and 11-3 overall in games when it recorded over 22.1 points last year.
- The Saints racked up 22.6 more yards per game (376.4) than the Patriots allowed per contest (353.8) last season.
- When New Orleans totaled more than 353.8 yards last season, the team was 6-6 against the spread and 9-3 overall.
- Last year the Saints had 17 turnovers, five fewer than the Patriots had takeaways (22).
Home and road insights
- New England was 5-3 overall, and 5-3 against the spread, at home last season.
- The Patriots were 3-2 ATS as 3-point favorites or greater at home last season.
- In eight home games last season, New England hit the over twice.
- Last season, Patriots home games averaged 44.9 points, 2.9 more than this matchup's over/under (42).
- New Orleans was 5-3 against the spread, and 6-2 overall, away from home last season.
- On the road, as 3-point underdogs or more, the Saints were 4-3 ATS.
- In eight road games last year, New Orleans went over the total four times.
- The average point total in Saints away games last season was 45.4 points, 3.4 more than this matchup's over/under (42).
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