Pittsburgh vs. Clemson College Football Odds, Plays and Insights


Check out odds, insights and more in our betting preview for the Pittsburgh Panthers vs. Clemson Tigers college football matchup on October 23, 2021.

Oct 16, 2021; Blacksburg, Virginia, USA; Pittsburgh Panthers quarterback Kenny Pickett (8) throws a pass during the second half against the Virginia Tech Hokies at Lane Stadium. Mandatory Credit: Reinhold Matay-USA TODAY Sports

The No. 23 Pittsburgh Panthers (5-1, 0-0 ACC) bring the second-ranked scoring offense in college football into a matchup with the Clemson Tigers (4-2, 0-0 ACC), who have the No. 2 scoring defense, on Saturday, October 23, 2021. The Panthers are 3.5-point favorites. The total is 47.5 points for this game.

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Odds for Pittsburgh vs. Clemson

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Over/Under Insights

  • Pittsburgh and its opponents have gone over the current 47.5-point total in five of six games this season.
  • Clemson's games have gone over 47.5 points in two opportunities this season.
  • The two teams combine to average 68.8 points per game, 21.3 more than the total in this contest.
  • This contest's total is 15 points more than the 32.5 these two squads combine to surrender per game this season.
  • The average total in Panthers games this season is 56.2, 8.7 points above Saturday's total of 47.5.
  • In 2021, games involving the Tigers have averaged a total of 49.6 points, 2.1 more than the set over/under in this contest.

Pittsburgh Stats and Trends

  • Pittsburgh is 5-1-0 against the spread this year.
  • The Panthers have been favored by 3.5 points or more five times this season and are 4-1 ATS in those contests.
  • Pittsburgh has eclipsed the over/under in 83.3% of its opportunities this year (five times over six games with a set point total).
  • This year, the Panthers rack up 35.8 more points per game (48.3) than the Tigers allow (12.5).
  • When Pittsburgh records more than 12.5 points, it is 5-1 against the spread and 5-1 overall.
  • The Panthers collect 530.3 yards per game, 213.8 more yards than the 316.5 the Tigers allow per contest.
  • When Pittsburgh churns out more than 316.5 yards, the team is 5-1 against the spread and 5-1 overall.
  • This year, the Panthers have five turnovers, three fewer than the Tigers have takeaways (8).
  • Find the latest spread and moneyline odds for Pittsburgh at SISportsbook.

Clemson Stats and Trends

  • Thus far this year Clemson is winless against the spread.
  • Clemson's games this year have hit the over on one of six set point totals (16.7%).
  • The Tigers rack up just 0.5 more points per game (20.5) than the Panthers give up (20).
  • Clemson is 0-2 against the spread and 1-1 overall in games when it puts up more than 20 points.
  • The Tigers collect only three more yards per game (322.3) than the Panthers give up (319.3).
  • When Clemson totals over 319.3 yards, the team is 0-2 against the spread and 2-0 overall.
  • The Tigers have six giveaways this season, while the Panthers have nine takeaways .
  • Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.

Season Stats