Check out odds, insights and more in our betting preview for the Purdue Boilermakers vs. Illinois Fighting Illini college football matchup on September 25, 2021.

The Purdue Boilermakers (2-1, 0-0 Big Ten) are 11-point favorites when they host the Illinois Fighting Illini (1-3, 0-0 Big Ten) in a Big Ten matchup on Saturday, September 25, 2021 at Ross-Ade Stadium. The game has a 53-point over/under.
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Odds for Purdue vs. Illinois
Odds courtesy of SI Sportsbook.
Over/Under Insights
- Purdue and its opponents have not yet combined for more than 53 points in a game this season.
- Illinois' games have gone over 53 points in two opportunities this season.
- The two teams combine to score 53.5 points per game, 0.5 more than the total in this contest.
- The 46.3 combined points per game that these two squads have allowed this season are 6.7 fewer than the 53 over/under in this contest.
- The average total in Boilermakers games this season is 60.3, 7.3 points more than Saturday's over/under of 53.
- In 2021, games involving the Fighting Illini have averaged a total of 56.3 points, 3.3 more than the set total in this contest.
Purdue Stats and Trends
- Thus far this year Purdue has two wins against the spread.
- The Boilermakers have been favored by 11 points or more once this season and covered the spread.
- Purdue's games this year have yet to go over the total in three opportunities.
- The Boilermakers average just 0.4 more points per game (30.7) than the Fighting Illini allow (30.3).
- The Boilermakers rack up 44.5 fewer yards per game (437.0), than the Fighting Illini allow per outing (481.5).
- This year, the Boilermakers have three turnovers, three fewer than the Fighting Illini have takeaways (6).
- Find the latest spread and moneyline odds for Purdue at SISportsbook.
Illinois Stats and Trends
- Illinois has two wins against the spread in four games this year.
- Illinois' games this year have hit the over on two of four set point totals (50%).
- The Fighting Illini put up 22.8 points per game, 6.8 more than the Boilermakers allow (16.0).
- Illinois is 2-1 against the spread and 1-2 overall when the team puts up more than 16.0 points.
- The Fighting Illini average 43.8 more yards per game (353.5) than the Boilermakers give up per matchup (309.7).
- Illinois is 2-2 against the spread and 1-3 overall when the team totals over 309.7 yards.
- The Fighting Illini have turned the ball over five times this season, three more turnovers than the Boilermakers have forced (2).
- Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.