Check out odds, insights and more in our betting preview for the Wyoming Cowboys vs. UConn Huskies college football matchup on September 25, 2021.

The UConn Huskies (0-4) are massive 30.5-point underdogs on Saturday, September 25, 2021 against the Wyoming Cowboys (3-0). The game has a 54-point over/under.
For more great betting and fantasy insight, join the SI Winners Club Newsletter.
Odds for Wyoming vs. UConn
Odds courtesy of SI Sportsbook.
Over/Under Insights
- UConn's games have gone over 54 points in only one opportunity this season.
- The combined points per game average of the two teams, 50.3, is 3.7 points fewer than Saturday's over/under.
- This contest's total is 15.7 points lower than the 69.7 these two squads combine to give up per game in 2021.
- The Cowboys and their opponents score an average of 48.8 points per game, 5.2 fewer than Saturday's total.
- The 54-point total for this game is 2.0 points below the 56.0 points per game average total in Huskies games this season.
Wyoming Stats and Trends
- Wyoming has covered the spread once this year.
- This year, the Cowboys put up 8.0 fewer points per game (38.0) than the Huskies allow (46.0).
- The Cowboys rack up 118.5 fewer yards per game (373.3), than the Huskies allow per outing (491.8).
- This year, the Cowboys have turned the ball over two times, while the Huskies have forced two.
- Find the latest spread and moneyline odds for Wyoming at SISportsbook.
UConn Stats and Trends
- UConn has one win against the spread in four games this year.
- The Huskies have covered the spread once this season when underdogs by 30.5 points or more (in two chances).
- UConn's games this year have hit the over on one of three set point totals (33.3%).
- This year the Huskies average 11.4 fewer points per game (12.3) than the Cowboys give up (23.7).
- The Huskies rack up 204.3 yards per game, 148.4 fewer yards than the 352.7 the Cowboys give up.
- The Huskies have seven giveaways this season, while the Cowboys have seven takeaways .
- Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.