The Bills are large road favorites on Thanksgiving against the Lions.
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The Vikings are small home favorites against the Patriots on Thanksgiving as they look to rebound from their loss to the Cowboys.
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The Cowboys are favored by more than a touchdown against the Giants at home on Thanksgiving.
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The Titans are home dogs in what may be a preview of a possible playoff matchup between these two top AFC teams.
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The Commanders are favored at home in Week 12 against the Falcons in a battle of playoff hopefuls.
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